Selected Publications

Adan C. Jirmo, Richard C. Koya, Bala Sai Sundarasetty, Mudita Pincha, Guann-Yi Yu, Michael Lai, Rakesh Bakshi, Verena Schlaphoff, Jan Grabowski, Georg Behrens, Heiner Wedemeyer, Renata Stripecke. Monocytes transduced with lentiviral vectors expressing hepatitis C virus non-structural proteins and differentiated into dendritic cells stimulate multi-antigenic CD8⁺ T cell responses. Vaccine 28 (2010) 922-933
PubMed I full text (PDF)

Mudita Pincha, Bala Sai Sundarasetty, Renata Stripecke. Lentiviral vectors for immunization: an inflammatory field. Vaccines 9(3), xxx-xxx (2010)
PubMed I full text (PDF)

Köchling J, Prada J, Bahrami M, Stripecke R, Seeger K, Henze G, Wittig B, Schmidt M. Anti-tumor effect of DNA-based vaccination and dSLIM immunomodulatory molecules in mice with Ph(+) acute lymphoblastic leukaemia. Vaccine. 2008 Aug 26;26(36):4669-4675. Epub 2008 Jul 17.
PubMed

Sarafian T, Montes C, Harui A, Beedanagari SR, Kiertscher S, Stripecke R, Hossepian D, Kitchen C, Kern R, Belperio J, Roth MD. Clarifying CB2 receptor-dependent and independent effects of THC on human lung epithelial cells. Toxicol Appl Pharmacol. 2008 May 9. [Epub ahead of print]
PubMed

Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, Schmid I, Shankar DB, Kasahara N, Stripecke R, Bhatia R, Landaw EM, Sakamoto KM. CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Blood. 2008 Feb 1;111(3):1182-92. Epub 2007 Nov 1.
PubMed

Kimura T., Koya RC., Anselmi L, Sternini C., Wang H., Comin-Anduix B., Prins R., Faure-Kumar E., Cui Y., Rozengurt N., Kasahara N. and Stripecke R (2007). Lentiviral Vectors with CMV or MHCII Promoters administered in vivo: Immune reactivity versus persistence of expression. Mol Ther. 15(7):1390-9.
PubMed I full text (PDF)

Koya R., Kimura T., Ribas A., Rozengurt N., Lawson GW, Faure-Kumar E., Wang H-J, Herschmann H., Kasahara K. and Stripecke R (2007). Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Mol Ther. 15(5):971-80.
PubMed I full text (PDF)

Prins, R.M., Craft N., Bruhn, K., Khan-Farooqi, H., Koya, R., Stripecke, R., Miller, J.F. and Liau, L.M. (2006). The Toll-like receptor agonist, imiquimod, enhances dendritic cell survival and promotes tumor antigen-specific T cell priming: relation to CNS anti-tumor immunity. J. Immunology 176(1):157-64.
PubMed I full text (PDF)

Rudolph, C, Hegazy, AN, von Neuhoff, N., Steinemann, D., Schröck, E, Stripecke, R., Klein, C., Schlegelberger, B (2005). Cytogenetic characterization of a BCR-ABL transduced mouse cell line. Cancer Genetics and Cytogenetics 161:51-56.
PubMed I full text (PDF)

Koya, RC, Weber JS, Kasahara, N, Lau, R, Levine, AM and Stripecke, R. (2004). Making Dendritic Cells from Inside-Out: lentiviral vector-mediated gene delivery of GM-CSF and IL-4 into CD14+ monocytes generates DCs in vitro. Human Gene Therapy, 15:733-48.
PubMed I full text (PDF)

Koya R.C., Kasahara, N. Favaro, P.M.B., Lau, R., Weber, J.S. and Stripecke, R. (2003). Potent maturation of dendritic cells after CD40L gene lentiviral gene delivery. J. Immunotherapy. 26 (5):451-460.
PubMed I full text (PDF)

Stripecke, R., Koya, R.C., Ta, H.C., Kasahara, N. and Levine, A.M. (2003). Use of lentiviral vectors for leukemia gene therapy: Combinatorial gene delivery of immunomodulators into leukemia cells by state-of –the-art vectors. Blood Cells, Molecules and Diseases 31:28-37.
PubMed I full text (PDF)

Koya R.C., Kasahara N., Pullarkat V., Levine A.M. and Stripecke R. (2002). Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses. Leukemia; 16 (9): 1645-1654.
PubMed

Stripecke, R., Cardoso, A. Pepper, K.A., Skelton, D.C., Xu, X.-J., Mascarenhas, L., Weinberg, K.I., Nadler, L.M. and Kohn, D.B. (2000). Lentiviral vectors for efficient gene delivery and expression of CD80 and granulocyte-macrophage-colony stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce anti-leukemia immune responses. Blood.; 96: 1417-1326.
PubMed I full text (PDF)

Stripecke, R., Skelton, D.C., Shimada, H., Pattengale, P. and Kohn, D.B. (1999). Combination of CD80 and GM-CSF co-expression by a leukemia cell vaccine: pre-clinical studies in a murine model recapitulating Philadelphia chromosome positive Acute Lymphoblastic Leukemia in mice. Hum. Gene Ther.; 10:2118-2122.
PubMed

Stripecke, R., Villacres, M.C, Skelton, D.C., Satake, N., Halene, S. and Kohn, D.B. (1999) Immune responses against enhanced green fluorescent protein: implications for gene therapy. Gene Ther.; 6(7):1305-1312.
PubMed

Case, S.S, Price, M.A., Jordan, C.T., Xu, D., Bauer, G., JinYu, X., Stripecke, R., Naldini, L., Kohn, D.B, and Crooks, G.M (1999). Stable transduction of quiescent CD34+CD38- human hematopoietic cells by HIV-based lentiviral vectors. Proc. Nat. Acad. Scien. USA, 96: 2988-2933.
PubMed

Reviews

Stripecke, R., Levine, A.M., Pullarkat, V. and Cardoso A.A. (2002) Immunotherapy with acute leukemia cells modified into antigen presenting cells: ex vivo culture and gene transfer methods. Leukemia; 16 (10): 1974-83.
PubMed

Chapters

Stripecke, R., Kasahara, N. Lentiviral and Retroviral Vector Systems. Gene Therapy for Cancer. Dr. Kelly K. Hunt, ed.

Stripecke, R. Lentiviral Vector-Mediated Genetic Programming of Mouse and Human Dendritic Cells. Methods in Molecular Medicine. Genetic modification of hematopoietic cells. Dr. Christopher Baum, ed.

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